Aztec
The manuscript was a translation from a Nahuatl original based on the work of Aztec physicians, composed in Santa Cruz, Mexico, and then sent to Europe. The 1552 manuscript is the first illustrated and descriptive scientific text of the vast body of Nahua medicine, experience, pharmacological remedies, medicinal plants and botany produced in the Americas. It is the work of two Aztec Indians, Martinus de la Cruz, a native physician who composed the work in Aztec, and another Indian, Juannes Badianus, who translated the text into Latin. it shows no traces of European influence.