Adding some more points in above answer.
One of the major drawbacks of an OFDMA system is that the transformation of a complex symbol mapped sequence (e.g. BPSK, QPSK, etc.) onto a small set of sub-carriers produces time sequences that have high PAPR (Peak-to-Average Power Ratio).
PAPR is the ratio between the maximum power and the average power This results in requirements for expensive transmission amplifiers and furthermore lead to high power consumption. Both effects are -particularly on terminal side unwanted.
It is thus a major design goal to limit this effect for the UL direction.
In order to reduce the PAPR a variant of OFDMA is used. It is called SC-FDMA (Single Carrier Frequency Division Multiple Access). SC-FDMA works according to the following mechanism, described for the associated transmitter structure. SC-FDMA is the method of choice for EUTRAN in the uplink direction.