You need to define your Netezza server properties inside Informatica's ODBC directory, something like below
[NZ_CONNECTION_NAME]
Driver = /opt/informatica/nz/lib/libnzsqlodbc3.so
Description = NetezzaSQL ODBC
Servername = nz_host_name_or_ip_address
Port = 5480
Database = group_generic_dims
Username = nz_db_username
Password = nz_db_password
CancelAsFreeStmt = false
CommLog = false
Ksqo = false
Lie = false
Optimizer = false
Parse = false
PreFetch = 256
Protocol = 7.0
ReadOnly = false
ShowSystemTables = false
Socket = 16384
DateFormat = 1
TranslationDLL =
Make sure you're pointing to the right libnzsqlodbc.so file (the driver).