If I got your question then your query is about what things are considered while sending "Initial UE Message" to a particular MME when an eNodeB is already connected to multiple MMEs of a pool.
If you go through the content of RRC Connection Setup Complete message (3GPP TS 36.331), it may contain "RegisteredMME" information element. When eNodeB receives this optional IE (Registered MME) within the RRC Connection Setup Complete message, it sends Initial UE message (3GPP TS 36.413) to MME based on this registered MME information. If Registered MME information is not received then eNodeB does load balancing , selects a MME and forward Initial UE message to the selected MME.